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Barbara Young

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Lynn Young, David Vismer, Matthew J. McAuliffe, Samson W. Tu, Lakshika Tennakoon, Amar K. Das, Vadim Astakhov, Amarnath Gupta, Jeffrey S. Grethe, and Maryann E. Martone, "Ontology Driven Data Integration for Autism Research",  22 nd IEEE International Symposium on Computer-Based Medical Systems, submission   (Accepted)
[Abstract] [Full Article]
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Nishizuka S, Ramalingam S, Spurrier B, Washburn FL, Krishna R, Honkanen P, Young L, Shimura T, Steeg PS, Austin J "Quantitative Protein Network Monitoring in Response to DNA Damage." J Proteome Res.  
[Abstract] [Full Article]
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Kovanen PE, Bernard J, Al-Shami A, Liu C, Bollenbacker-Reilley J, Young L, Pise-Masison C, Spolski R, Leonard WJ "T-Cell Development and Function are Modulated by Dual Specificity Phosphate DUSP5" J Biol Chem.  283(25):17362-9   
[Abstract]  [PubMed]
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Sundhar Ramalingam, Peter Honkanen, Lynn Young, Tsutomu Shimura, John Austin, Patricia S. Steeg, and Satoshi Nishizuka Quantitative Assessment of the p53-Mdm2 Feedback Loop Using Protein Lysate Microarray Cancer Research.  67(13), 6247-52  
[Abstract] [Full Article]
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Petricoin III, E.F., Bichsel,V.E., Calvert,V.S., Espina,V., Winters,W., Young, L., Belluco,C., Trock, B.J., Lippman, M., Fishman, D.A., Sgroi, D.C.,Munson, P.J., Esserman, L.J., and Liotta, L.A. "Mapping Molecular Networks Using Proteomics:A Vision for Patient-Tailored Combination Therapy" Journal of Clinical Oncology. 23:3614-3621.   
[Abstract] [Full Article]
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Kovanen, P.E.,Young, L., Al-Shami1, A., Rovella,V., Pise-Masison,C.A, Radonovich, M.F., Powell, J., Fu, J., Brady, J.N., Munson, P.J., and Leonard,W.J. "Global analysis of IL-2 target genes: identificationof chromosomal clusters of expressed genes" International Immunology, Vol. 17, No. 8, pp. 10091021   
[Abstract] [Full Article]
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Gius D, Cui H, Bradbury M, Cook J, Smart DK, Zhao S, Young L, Brandenburg SA, Hu Y, Bisht KS, Ho aS, Mattson D, Sun L, Munson PJ, Chuang EY, Mitchel JB, Feinberg AP
"Distinct Effects on Gene Expression of Chemical and Genetic Manipulation of the Cancer Epigenome Revealed by a Multimodality Approach." Cancer Cell. 6(4):361-71  
[PubMed]
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Boissinot S, Entezam A, Young L, Munson PJ, Furano AV
"The insertional history of an active family of L1 retrotransposons in humans." Genome Res. 14(7):1221-31  
[PubMed]
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Nishizuka S, Chen ST, Gwadry FG, Alexander J, Major SM, Scherf U, Reinhold WC, Waltham M, Charboneau L, Young L, Bussey KJ, Kim S, Lababidi S, Lee JK, Pittaluga S, Scudiero DA, Sausville EA, Munson PJ, Petricoin EF 3rd, Liotta LA, Hewitt SM, Raffeld M, Weinstein JN
"Diagnostic markers that distinguish colon and ovarian adenocarcinomas: identification by genomic, proteomic, and tissue array profiling." Cancer Res. 63(17):5243-50.  
[PubMed]
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Daoud SS, Munson PJ, Reinhold W, Young L, Prabhu VV, Yu Q, LaRose J, Kohn KW, Weinstein JN, Pommier Y
"Impact of p53 knockout and topotecan treatment on gene expression profiles in human colon carcinoma cells: a pharmacogenomic study." Cancer Res. 63(11):2782-93  
[PubMed]
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Nishizuka, S., Charboneau, L., Young, L., Kauor, S., Reinhold, W. C., Waltham, M., Kouros-Mehr, H., Bussey, K. J., Lee, J. K., Espina, V., Munson, P. J.,
"Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays." PNAS 100(24): 14229-14234  
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Liotta, L. A., Espina, V., Mehta, A. I., Calvert, V., Rosenblatt, K., Geho, D., Munson, P. J., Young, L., Wulfkuhle, J., Petricoin, E. F.,
"Protein microarrays: Meeting Analytical challenges for clinical applications." Cancer Cell 3: 317-324  
[PubMed]
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Young, L., P. E. Kovanen, et al.
"Scanning the Human Genome Sequence for Clusters of Expressed Genes." Presented at the TGIR conference in Savannah Georgia in September 2003  
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Grove, A. D., Prabhu, V., Young, B. L., Lee, F. C., Kulpa, V., Munson, P. J., Kohn, E. C.
"Both Protein Activation and Gene Expression Are Involved in Early Vascular Tub Formation in Vitro." Clinical Cancer Research 2002 8: 3019-3026  
[PubMed]
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Dagdug, L. and L. Young
"A Theoretical framework for the study of the melting transition of DNA using the stochastic matrix method." Physical Review E.  
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Liu, K., Li, Y., Prabhu, V. V., Young, B. L., Becker, K. G., Munson, P. J., Weng, N.
"Augmentation in Expression of Activation-Induced Genes Differentiates Memory from Naive CD4+ T Cells and Is a Molecular Mechanism for Enhanced Cellular Response of Memory CD4+ T Cells." The American Association of Immunologists 7335-7344  
[PubMed]
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Grove, A.D., Lee, F.C., Prabhu, V.V., Young, B.L., Munson, P.J., Kohn, E.C.
"In Validation and application of nylon cDNA microarrays in the analysis of endothelial cell gene expression during tubulogenesis (abstract)" AACR  

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